Posts Tagged ‘irritation’
Why Chemical Patches to Quit Smoking Cause Itching?
The TRPA1 (Transient Receptor Potential Cation Channel, member A1) is an ion channel, found in the skin and inside the nose and mouth.
A study on the effects of nicotine published Sunday in Nature Neuroscience could explain why the chemical patches and other alternative treatments to quit smoking often cause irritation and itching.
This finding could help develop treatments to stop smoking without many side effects. Nicotine compound organic plant alkaloid found in the snuff, active in the body a channel that is known to be associated with inflammatory reactions.
This ion channel, which is in the skin and inside the nose and mouth, could be the source of irritation as a side effect, they cause the snuff replacement therapy.
It was thought that itching and rashes that lead to nicotine patches and other treatments were due to stimulation of nicotinic receptors in the nerves that transmit painful stimuli from the skin and tissue lining the nose and mouth .
However, in mice, nicotine also directly activated TRPA1, the channel associated with the transmission of information on irritants and inflammatory pain. TRPA1-deficient mice did not show any reaction of irritation with nicotine administered nasally.
This finding could help develop treatments to stop smoking without many side effects such as these.
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What is Sinusitis?
If you take a few days congested or stuffy nose and waking up with headaches and swollen eyes, you may have sinusitis. Sinusitis is annoying and may even be painful at times, but usually not severe.
Sinusitis is the medical term used to describe inflammation (irritation and swelling) of the sinuses. Usually caused by infection.
The sinuses are bony cavities filled with moist air inside the bones of the face around the nose. The frontal sinuses are in the area that is near the eyebrows, the maxillary sinuses are inside the cheek (the cheek bones). Ethmoid sinuses between the eyes, and sphenoid sinus behind the ethmoid sinuses.
When we’re healthy, sinuses are filled with air, which causes facial bones are less dense and lighter. The sinuses also influence how the voice sounds like.
Infections by viruses or bacteria, or both at once-can cause sinusitis. Usually when a person has a cold sore breasts. This is viral sinusitis. Allergies can also trigger the long run, a sinus infection.
When nasal congestion (stuffiness) associated with the common cold or an allergy does not allow the sinuses to drain properly, bacteria can become trapped inside the sinuses, leading to bacterial sinusitis.
Those with bacterial sinusitis usually found worse than those affected by a viral sinusitis. A person with bacterial sinusitis usually will have more facial pain and swelling that you have viral sinusitis, and may also have fever.
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