Posts Tagged ‘smoking’
Why Chemical Patches to Quit Smoking Cause Itching?
The TRPA1 (Transient Receptor Potential Cation Channel, member A1) is an ion channel, found in the skin and inside the nose and mouth.
A study on the effects of nicotine published Sunday in Nature Neuroscience could explain why the chemical patches and other alternative treatments to quit smoking often cause irritation and itching.
This finding could help develop treatments to stop smoking without many side effects. Nicotine compound organic plant alkaloid found in the snuff, active in the body a channel that is known to be associated with inflammatory reactions.
This ion channel, which is in the skin and inside the nose and mouth, could be the source of irritation as a side effect, they cause the snuff replacement therapy.
It was thought that itching and rashes that lead to nicotine patches and other treatments were due to stimulation of nicotinic receptors in the nerves that transmit painful stimuli from the skin and tissue lining the nose and mouth .
However, in mice, nicotine also directly activated TRPA1, the channel associated with the transmission of information on irritants and inflammatory pain. TRPA1-deficient mice did not show any reaction of irritation with nicotine administered nasally.
This finding could help develop treatments to stop smoking without many side effects such as these.
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Is Cancer Hereditary?
When we speak of hereditary cancer specialists should be clarified that relate to the predisposition to disease in the event that the parent suffering from a particular type of tumor. But that does not mean that the person is sentenced to have the condition.
There are many types of cancer, and some of them are clearly linked to environmental factors in lung cancer and smoking, or skin cancer and excessive sun exposure. Others, however, are linked to hereditary issues. In the case of breast cancer, for example, the daughters of women who have suffered are more predisposed to suffer.
It should be noted that cancer is a broad group of diseases characterized by uncontrolled growth of abnormal cells. While normal cells reproduce and grow in an orderly fashion with a purpose-as, for example, closing wounds, cancer cells grow without special reason. They multiply uncontrollably destroying normal tissues and can spread to different parts of the body.
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